Thiocolchicoside Injection

Thiocolchicoside Injection is a muscle relaxant primarily prescribed to relieve pain and muscle spasms related to spinal conditions and post-surgical recovery. It acts on the central nervous system to reduce involuntary muscle contractions, providing both relaxation and pain relief.

Thiocolchicoside Injection is a semi-synthetic colchicoside derivative, which is obtained from the Colchicum autumnale plant. It is identified as a muscle relaxant and an anti-inflammatory drug. It is generally applied for its analgesic and muscle-relaxing effects, particularly in painful musculoskeletal disorders.

What are the Benefits and Uses of Thiocolchicoside Injection ?

Thiocolchicoside Injection is mainly employed as a muscle relaxant in the relief of pain and stiffness due to spasms of muscles. It is frequently prescribed for the treatment of back pain, cervical spondylitis, torticollis (wry neck), and sciatica. It is useful in controlling post-operative muscle pain and injuries with inflammation or muscle strain. Its analgesic and anti-inflammatory actions render it useful in the control of musculoskeletal disorders.

Conditions Thiocolchicoside Injection Treats

• Acute and chronic back pain
• Cervical spondylosis
• Lumbar spondylosis
• Torticollis (twisted neck)
• Sciatica
• Spasm of muscles caused by trauma or strain
• Secondary Uses of Thiocolchicoside
• Postoperative pain management following orthopedic surgery
• Adjunctive treatment of inflammatory diseases of the vertebral spine

How Does Thiocolchicoside Injection Work?

Thiocolchicoside Injection acts by binding to the GABA-A and glycine receptors in the central nervous system. These receptors are implicated in the control and relaxation of muscles. Through modulating these neurotransmitter mechanisms, Thiocolchicoside inhibits spasms and stiffness of muscles, with resultant easier movement and reduced pain.

Thiocolchicoside Dosage

The usual adult dose of Thiocolchicoside Injection is 8 mg orally every 12 hours, with a limit of 16 mg per day. The drug is normally prescribed for short-term treatments, usually not exceeding seven consecutive days. It may be administered with food or milk to reduce gastrointestinal distress. Always heed your physician’s advice for safe and effective use.

Usual Adult Dose: 8 mg orally every 12 hours.

Maximum Daily Dose: 16 mg.

Duration: Not to be used for more than seven consecutive days except if prescribed.

Administration Hints: With food or milk to minimise stomach discomfort.

What Should I Do If I Miss a Dose?

If you forget a dose, take it as soon as possible. If your next scheduled dose is about to be taken, omit the one you have missed. Do not double the dose for the missed one. Ask your doctor or pharmacist if in doubt.

What to Do in the Event of an Overdose?

Symptoms of Overdose May Include

• Excessive sleepiness
• Confusion or restlessness
• Vomiting
• Neurological symptoms (e.g., seizures)
• In the event of suspected overdose, obtain immediate medical help, even if signs and symptoms are not promptly evident.
• Seek a second opinion from qualified professionals and make informed, confident decisions.
• Obtain Second Opinion

What are the Side Effects of Thiocolchicoside Injection?

Thiocolchicoside Injection can produce a few side effects, most of which are transient and mild. Some frequent side effects are drowsiness, headache, dizziness, nausea, vomiting, diarrhea, and dryness of the mouth. Some individuals may also develop allergic reactions like skin rashes, itching, or swelling of the face. In exceptional instances, severe side effects like jaundice (yellowing of the eyes or skin) or excessive sensitivity to the sun (photosensitivity) have been reported. Any severe, rare, or long-lasting symptoms should be reported to a healthcare professional immediately.

Common Side Effects

• Drowsiness
• Headache
• Dizziness
• Dry mouth
• Diarrhea
• Nausea or vomiting
• Skin rash or itching
• Serious But Rare Side Effects
• Yellowing of the eyes or skin (jaundice)
• Swelling of the face
• Fainting
• Sensitivity to light

Severe allergic reactions (shortness of breath, swelling of face/tongue)

Note: Report any worsening or persistent symptoms to your doctor.

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Precautions and Warnings

Thiocolchicoside Injection is to be used cautiously in some patients. 

It is contraindicated in children below 16 years of age, pregnant and lactating women, and patients with kidney or liver disease. Seizure and neurological disorder patients must also stay away from this drug, as it can exacerbate symptoms. Alcohol consumption is prohibited during the drug because there is a higher chance of drowsiness and sedation. The drug should only be used for a long duration or in high doses under close medical supervision, as it will heighten the risk of complications.

Who Should Stay Away From This Medicine ?

• Pregnant and lactating women
• Children below 16 years old
• Patients with severe kidney or liver disease
• Conditions Requiring Caution
• Renal or hepatic impairment
• History of convulsions
• Gastrointestinal disturbances

Frequently Asked Questions ( FAQ )

Are There Any Age Limitations to Using Thiocolchicoside?

Yes, and it is not advisable for use in persons below the age of 16 because of safety issues.

How Should Thiocolchicoside Injection Be Stored?

Thiocolchicoside Injection must be stored in a dry, cool place with protection from sunlight, heat, and moisture. Ideal storage temperature is 20°C to 25°C (68°F to 77°F). It must not be frozen or kept in a damp area such as a bathroom. Always store the drug out of the reach of children and pets to avoid accidental ingestion. Proper storage ensures the effectiveness and safety of the medicine.

• Recommended Storage Temperature
• Store at room temperature, preferably between 20°C to 25°C (68°F to 77°F).
• What If Thiocolchicoside Is Not Stored Correctly?
• It may lose its effectiveness after exposure to moisture, heat, or sunlight.
• Do not freeze.
• Store out of reach of children and pets.